Each treatment typically lasts up to
3-6 months and can be repeated as long as your condition responds to BOTOX® and
you do not have any serious allergic reactions or other significant side
effects. BOTOX® has been used for more than 15 years to help patients worldwide,
and although formal, long-term clinical evaluations have not been conducted, its
safety in long-term use has been well established.
Although most people continue to respond to BOTOX® injections, some people have
experienced a diminished response over time. There may be several explanations
for this:
-
Changes in your condition - If the
pattern of your muscle activity changes, your healthcare provider may need to
inject new muscles and/or change your dose. Identifying and injecting the
affected muscle can be difficult, complicated by the changing pattern of
muscle involvement and progression of the disorder.
-
Setting appropriate expectations -
You may believe your first BOTOX® injection was more helpful than subsequent
injections. That's because your condition was perhaps quite severe when you
had your first injection. Subsequent injections are usually given before your
condition becomes that severe again. Therefore, the relief you experienced
with subsequent injections may not have been as dramatic as the first time.
-
Antibody formation - When foreign
proteins, like botulinum toxins, enter your body, antibodies may form. If
antibodies to botulinum toxin develop, you may no longer respond to treatment.